Results That Last. Not Just Until Your Next Appointment.
Bellafill is the only FDA-approved biostimulator dermal filler clinically proven to last up to 5 years, the longest-studied dermal filler ever tested.
Most fillers fade in months, leaving you back in the treatment chair before you know it. Bellafill works differently. It provides immediate correction while stimulating your own collagen to build lasting results over time, with no constant maintenance, no repeat appointments every few months.
The Filler That Works With Your Body - Not Against Time
Bellafill is a biostimulatory injectable dermal filler FDA-approved to correct nasolabial folds (the lines that run from the nose to the corners of the mouth) and moderate to severe atrophic acne scars on the cheek in patients 21 and older.
Unlike hyaluronic acid fillers that simply fill a space and slowly break down, Bellafill is built around two clinically proven components that work together:
80% smooth collagen gel provides immediate volume and visible correction the moment treatment is complete. You walk out of the office looking smoother.
20% PMMA (polymethylmethacrylate) microspheres are suspended within the collagen gel. As your body naturally absorbs the collagen over time, these microspheres remain and form a supportive scaffold — stimulating your own natural collagen to grow around them for long-term correction that holds.
The result: results you see immediately, maintained by your own biology.
Two Proven Indications. One Long-Lasting Solution.
Nasolabial Folds (Smile Lines)
Nasolabial folds are the lines that extend from the sides of the nose down to the corners of the mouth. They deepen with age as facial volume shifts and collagen breaks down. Bellafill was FDA-approved for nasolabial fold correction in 2006 and has been clinically validated in the largest and longest prospective dermal filler study ever completed: 1,008 patients followed for five full years.
Acne Scars
Acne scars can be one of the most difficult cosmetic concerns to address. Bellafill received FDA approval in December 2015 for the correction of moderate-to-severe, atrophic, distensible facial acne scars on the cheeks in patients over 21. In a double-blind, randomized, multicenter clinical trial, 64% of patients treated with Bellafill achieved treatment success at six months. compared to 33% in the control group. With a relaxed threshold of one-point improvement, 91% of treated scars showed measurable improvement.
Built Different. Backed by Data.
5 Years Proven safety and patient satisfaction established through the longest dermal filler study ever conducted.
1,008 Patients Enrolled in the five-year post-approval study, which is the largest sample size of any prospective dermal filler trial.
83% Of patients reported being satisfied or very satisfied with their results at the five-year mark.
Less Than 1% Of patients had an unresolved granuloma at study exit. All were mild to moderate and responded to standard medical treatment.
Bellafill’s rheological properties its firmness, elasticity, and viscosity are specifically engineered for high lifting capacity and precise placement. In a published engineering study, Bellafill demonstrated elasticity approximately 9.5 times greater than Juvederm Voluma and viscosity approximately 9.3 times greater. This means Bellafill holds its position after injection, provides structural support, and resists spreading into surrounding tissue.
Bellafill also contains PMMA, a biocompatible material used safely in medicine for over 65 years in applications including intraocular lenses and orthopedic bone cement. There are no published studies showing PMMA appears on radiographic imaging such as X-ray, CT, MRI, or PET scans, unlike many other commonly used fillers.
Sound Familiar? You May Have Filler Fatigue.
Of the approximately nine million people in the United States who have received dermal filler treatments, an estimated eight million experience what researchers have termed “filler fatigue,” the frustration and exhaustion of having to return for repeat injections every few months just to maintain results.
A Harris Poll survey found that longer-lasting fillers were the number one improvement filler patients wanted. Ninety percent of those surveyed said they would be interested in a five-year FDA-approved filler, and nearly nine in ten said they would continue going to their provider for other services if that provider offered a long-lasting collagen-building solution.
Bellafill is the only filler that has answered that demand — and the only one with FDA-approved safety and efficacy data to back it up for five full years.
Is Bellafill Right for You?
Bellafill may be an excellent option if you:
- Are 21 years of age or older?
- Are bothered by nasolabial folds (smile lines) and want a long-term correction without frequent touch-ups
- Have moderate to severe atrophic acne scars on the cheeks that have not responded adequately to other treatments
- Want to reduce the time, cost, and discomfort of repeat filler appointments
- Are you looking for a clinically proven, FDA-approved solution with a multi-year track record
Who Should Not Receive Bellafill: Bellafill is not suitable for patients who have had a positive reaction to the required Bellafill skin test, have a history of severe allergies or anaphylaxis, are allergic to bovine collagen or lidocaine, have bleeding disorders, or are prone to keloid or hypertrophic scarring. A mandatory skin test is required 4 weeks before your first treatment to confirm that you are not sensitive to bovine collagen in Bellafill.
If you are pregnant or breastfeeding, the safety of Bellafill has not been established, and treatment is not recommended.
Why Patients Choose alloClae
Consultation
We begin with a thorough one-on-one consultation with our team to assess your concerns, review your medical history, and determine whether Bellafill is the right fit for your goals. We take time to understand not just what you want to correct, but how you want to feel about your results.
Skin Test
Because Bellafill contains bovine collagen, a skin test is required approximately four weeks before your first treatment. A small amount of bovine collagen is injected under the skin of your forearm. You observe the test site daily and return four weeks later for evaluation. If the result is negative, you are cleared to proceed with treatment.
Treatment
Bellafill is administered using a fine needle with a linear threading technique, placing the filler in the deep dermis. The product contains lidocaine to minimize discomfort. Most patients find treatment well-tolerated. Sessions typically take 30 to 60 minutes. Depending on the degree of correction needed, one to three sessions may be recommended.
Recovery
There is no required downtime. You can resume normal activities immediately after treatment. Some patients experience temporary swelling, redness, bruising, tenderness, or minor lumpiness at the injection site. These side effects are typically mild and resolve within one to seven days. Patients should minimize sun exposure and avoid extreme temperatures until any initial redness or swelling has subsided.
Results
Correction is visible immediately following treatment. As the collagen component is gradually reabsorbed over the following weeks and months, the PMMA microspheres remain and stimulate your own natural collagen to continue the correction. Patient satisfaction in clinical studies remained consistently high from six months through the five-year mark, with 83% of patients still satisfied at year five.
Common Questions About Bellafill
The safety and effectiveness of Bellafill have been established for five years for nasolabial fold correction and for 12 months for acne scar correction. Bellafill is the only FDA-approved dermal filler with this length of proven data.
Yes. Bellafill provides immediate volume and lift. You will see visible correction as soon as you leave the office. Over time, as your body naturally absorbs the collagen carrier, your own collagen grows around the PMMA microspheres to maintain and support those results long-term.
Most patients require between one and three treatment sessions to achieve optimal correction. During your consultation, your provider will recommend the appropriate number of sessions based on your individual anatomy and goals. Touch-up sessions are scheduled at least 2 weeks apart.
No required downtime. Most patients return to normal activities immediately. You may experience mild, temporary swelling, redness, bruising, tenderness, or lumpiness that typically resolves within 1 to 7 days.
Bellafill has been proven safe in the largest and longest prospective dermal filler study ever completed: 1,008 patients followed for five years with no treatment-related serious adverse events. Its PMMA microspheres are made from a biocompatible material that has been safely used in medical devices for over 65 years.
Bellafill contains bovine collagen, so a mandatory skin test is required four weeks before your first treatment to confirm you are not sensitive to this ingredient. The test involves a small injection under the skin of your forearm. If the result is negative after four weeks, you are cleared for treatment.
The cost of Bellafill varies depending on the number of syringes and treatment sessions recommended by your provider. During your consultation, we will develop a personalized treatment plan tailored to your specific goals and budget.
Bellafill is FDA-approved specifically for nasolabial folds and moderate to severe atrophic facial acne scars on the cheek in patients over 21. It is not indicated for lip augmentation, the periocular area (such as the tear trough), or areas where concentric muscle movement is predominant.
Standard hyaluronic acid fillers like Juvederm and Restylane provide temporary correction that typically lasts six to eighteen months before being fully absorbed by the body. Bellafill is not absorbed; the PMMA microspheres remain permanently and stimulate your own collagen, providing correction that extends well beyond what any temporary filler can offer. Clinical data show that Bellafill’s results are maintained for 5 years, with 83% patient satisfaction.
Important Safety Information
You may experience temporary swelling, redness, pain, bruising, lumps/bumps, itching, and discoloration at the treatment site. These side effects are usually transient and typically resolve within 1 to 7 days. Less common side effects include rash and itching more than 48 hours after treatment, persistent swelling or redness, lumps/bumps, acne, and increased sensitivity at treatment sites.
Granulomas may occur infrequently and be treated by your licensed physician. Based on the 5-year Post Approval Study of nasolabial folds with 1,008 patients, the long-term safety of Bellafill has been established for up to 5 years.
For more safety information, please consult with your physician. Bellafill is a prescription-only product available only through licensed physicians.
Bellafill is indicated for the correction of nasolabial folds and moderate-to-severe, atrophic, distensible facial acne scars on the cheek in patients aged 21 years or older.
Patients who have had a positive reaction to the Bellafill Skin Test, have a history of severe allergies, have known bovine collagen allergies, are allergic to lidocaine, have bleeding disorders, or are prone to thick scar formation and/or excessive scarring should not receive Bellafill. The safety of Bellafill for use during pregnancy, breastfeeding, or in patients under 21 years of age has not been established.
Ready to Stop Repeating Yourself?
If you are tired of the cycle of temporary fillers that require constant upkeep, Bellafill may be the solution you have been looking for.
Our team at Signature Plastic Surgery will walk you through every step, from your initial consultation and skin test through your treatment and beyond.